US stock futures fell with investors on edge as Israel and Iran continued to trade strikes against a backdrop of shifting US trade policy and stubborn interest rates.

Futures on Wall Street have declined on Tuesday morning Indian time after an uneasily positive session to start the truncated week. The Dow futures are currently down 165 points, while the S&P 500 and Nasdaq futures are down 30 and 110 points respectively.

U.S. stock index futures edged lower on Tuesday as conflict in the Middle East entered its fifth day, dampening global investor confidence ahead of the Federal Reserve's upcoming policy meeting.

Markets are concerned about Iran's frequent threats to blockade the Strait of Hormuz, just as the US heads into peak summer demand season.

U.S. futures for the S&P 500 were down 0.6% and futures for the Dow Jones Industrial Average declined 0.7%. Changes in futures do not necessarily predict movements after the opening bell.

U.S. stock index futures edged higher on Monday as easing oil prices helped calm sentiment despite ongoing attacks between Iran and Israel and increased focus on the upcoming Federal Reserve meeting.

The missile exchanges dominate global market focus as it intensified fears of energy supply disruptions. West Texas Intermediate (WTI) crude futures climbed as high as $74.78 per barrel Sunday evening, but eased back to below $72.54 per barrel this morning, though that remains 11% above where it traded last Monday.

U.S. stock futures point higher, Victoria's Secret shares rise on a report that an activist investor is building a stake in the lingerie company, and EchoStar stock jumps on a report that President Donald Trump met with officials about the firm's spectrum licenses.

Stock futures rebounded slightly early Monday as the spike in oil prices due to the escalating conflict between Israel and Iran eased for a moment. Stock gains were muted as investors remained concerned about the rising geopolitical risk to the global economy.