The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers Cooper Kupp and Puka Nacua.

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

San Francisco 49ers running back Christian McCaffrey missed most of training camp and the entire preseason due to a calf strain and Achilles tendinitis, the latter of which kept him out of Week 1. On ...

Check out our Rams vs. 49ers how to watch guide to learn when they play and what free live streams are available ahead of ...

The spread has moved one point in the Rams’ direction since Monday, likely because of the 49ers’ recent injury news ...

Week 3 features some key games between 2-0 teams, including the Texans at the Vikings and the Chargers at the Steelers. And ...

Everything you need to know about the Rams' home game against the NFC West rival San Francisco 49ers, including start time, ...

The San Francisco 49ers and Los Angeles Rams will be missing top players because of injuries when they meet on Sunday in the ...

As the Los Angeles Rams gear up for a pivotal Week 3 matchup against the San Francisco 49ers, they have released their first ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle reported soreness in his hamstring after Wednesday’s practice.