Keyshawn Johnson breaks down Deebo Samuel’s claim that it's 'Now or Never' for the San Francisco 49ers to win the Super Bowl.

As the San Francisco 49ers set their sights on another deep playoff run this season, wide receiver Deebo Samuel is making one ...

After a walk-off win against the Cincinnati Bengals in Week 2, the two-time reigning Super Bowl champions sit pretty after ...

The San Francisco 49ers could lose some important pieces next offseason. Will the team be able to keep the core together?

All is right with the Minnesota Vikings after two games. They are a perfect 2-0, having defeated the New York Giants in the ...

Deebo Samuel’s calf injury puts the spotlight on the 49ers’ other stars amid a critical stretch on the schedule.

Arizona Cardinals is one of just two teams to have played every NFL season since the league began in 1920, but they still are ...

The 49ers just lost 23-17 on the road to the Minnesota Vikings. Here are the 49ers' grades for this embarrassment.

As of Sept. 19, the San Francisco 49ers' odds of winning the Super Bowl (+600) make them second-best in the NFL. In their last game, the 49ers were knocked off by the Minnesota Vikings 23-17.

There's no panic in the San Francisco 49ers locker room despite recent injuries and a disappointing Week 2 loss to the ...

Deebo Samuel is tired of falling short. He knows the San Francisco 49ers have had one of the best rosters in the NFL for ...