Police responded to the 6000 block of West Lake Road Drive, near Coquina Kentucky Drive and West Lake North Drive, just before 2 a.m. Sunday.
According to INDOT, the crash happened on Interstate 70 westbound, near the South Holt Road exit, just before 1 a.m. Sunday.
At least one person died early Sunday morning in a crash on Interstate 70 westbound on the southwest side of Indianapolis.