Ryan Reynolds/YouTube; ABC Photo Archives/Disney General Entertainment Content via Getty Ryan Reynolds in 'Doogie Howser M.D.' spoof; Neil Patrick Harris in a 1989 photo from the real thing More ...

And since Neil Patrick Harris is filling that role in the newly announced Marvel’s Deadpool VR, Reynolds responded exactly how you’d imagine: by taking over as Doogie Howser.

Step aside, Ryan Reynolds, because famed sitcom star Neil Patrick Harris will officially portray Marvel's infamous Merc with a Mouth in an upcoming VR game.

Ryan Reynolds isn't letting go of Deadpool without a fight — or at least some carefully plotted vengeance. After several years as the face, voice and personal cheerleader of the merc with a mouth, ...

Step aside, Ryan Reynolds, because famed sitcom star Neil Patrick Harris will officially portray Marvel's infamous Merc with a Mouth in an upcoming VR game.