The Baltimore Orioles (50-60) visit the Chicago Cubs (64-45) Saturday for the second game of their 3-game series. First pitch from Wrigley Field is set for 2:20 p.m. ET (FS1). Let's analyze BetMGM Sportsbook's MLB odds around the Orioles vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

The Orioles (+138 underdog on the moneyline to win) visit the Cubs (-164). The matchup on the mound for this contest is set with the Chicago Cubs looking to Colin Rea (8-5), and Brandon Young (0-5) taking the ball for the Baltimore Orioles.

Find the latest odds, spread and score prediction for the Baltimore Orioles vs. Chicago Cubs MLB game on ESPN to be played on August 2, 2025 on ESPN.

Gunnar Henderson hit a three-run homer in a four-run eighth inning and the Baltimore Orioles beat the Chicago Cubs 4-3 on Saturday for their seventh victory in 10 games. Jordan Westburg had an RBI single off Caleb Thielbar (2-3) in the eighth to end the Orioles’ scoreless streak at 18 innings.

Gunnar Henderson launched a three-run home run to give the Baltimore Orioles a late lead over the Chicago Cubs.

The Baltimore Orioles looked about as lifeless as they had all season. Enter Gunnar Henderson. With Baltimore entering the eighth inning Saturday mired an 18-inning scoreless streak and in danger of being shut out by the Chicago Cubs for the second straight day,