The Mona Lisa continues to captivate the world with its secrets. Every new study raises more questions than answers, keeping the fascination with this Renaissance masterpiece alive.

Dave J Hogan/Dave J Hogan/Getty Images When Tom Hanks found himself with his pants down in front of the iconic Mona Lisa painting while filming The Da Vinci Code, director Ron Howard couldn't help but laugh.

Tom Hanks is in a league of his own. The actor had an unusual experience at one of the most famous museums in the world when he ended up without pants in front of the Mona Lisa.

At a Happy Days reunion event held at MegaCon in Orlando on Friday, Feb. 7, director Ron Howard offered an anecdote about the behind-the-scenes of the film and how star Tom Hanks wound up with no pants on in front of the world's most revered work of art.