Leona is a city in Leon County, Texas, United States. The population was 151 at the 2020 census. According to the United States Census Bureā¦Leona is a city in Leon County, Texas, United States. The population was 151 at the 2020 census. According to the United States Census Bureau, the city has a total area of 2.2 square miles, all land. As of the census of 2000, there were 181 people, 71 households, and 48 families residing in the city. The population density was 83.2 inhabitants per square mile. There were 91 housing units at an average density of 41.8 per square mile. The racial makeup of the city was 83.43% White, 13.81% African American, 0.55% Asian, and 2.21% from two or more races. Hispanic or Latino of any race were 2.21% of the population.